Alpha-substituted fatty amines and nitrogen-containing heterocycles are widely found in numerous bioactive natural products, pharmaceutical molecules, and agrochemicals. A recent analysis of small ...
It’s hard to improve on a classic. But Richard Y. Liu was eager to take on that challenge. Cross-coupling reactions, including Suzuki-Miyaura coupling and Buchwald-Hartwig amination, are some of the ...
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Chemistry’s new era of smart reactions
From light-fueled, self-regenerating catalysts to biocompatible couplings in live cells, chemistry is entering a smarter, greener era. Researchers are merging computational insight, sustainable design ...
Researchers used a novel phosphate-activation reagent, 2-MeImIm-Cl, in an improved coupling reaction to increase the yield of ADP- or ATP-containing molecules. Unlike traditional reactions, the ...
Organic chemists have tended to avoid using water to host reactions, largely because their carbon-based molecules rarely dissolve in the liquid. Now, Burkhard König at the University of Regensburg has ...
A straightforward and reproducible synthesis pathway for a diverse range of ATP- and ADP-coupled biomolecules has been developed by modifying an established reagent. Researchers at the Institute for ...
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