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Q&A: How cryptic mitochondrial DNA mutations reveal a hidden layer of the aging process
New research published in Nature Communications into hidden mutations in mitochondrial DNA has uncovered how high mutational levels coincide with later life and link to aging markers. Mitochondria are ...
Scientists at The University of Texas at Austin have developed a revolutionary gene-editing method using bacterial retrons that can correct multiple disease-causing mutations at once. Unlike ...
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Single-dose base editing corrects PKD1 mutation and extends survival in ADPKD preclinical models
Mayo Clinic researchers have developed a promising gene-editing therapy that directly corrects a genetic mutation responsible for autosomal dominant polycystic kidney disease (ADPKD), the most common ...
As we age, our cells accumulate DNA mutations. If any of these mutations confer a growth advantage to a self-renewing or long-lived progenitor cell, its lineage can expand. The progenitor cells that ...
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