Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene ...

The team found that many variants linked to complex diseases are also associated with more unproductive splicing and decreased gene expression. So, they believe that better understanding its impact ...

DNA is the blueprint of life. Genes encode proteins and serve as the body's basic components. However, building a functioning ...

Propagation of expression noise from mRNA to protein level is influenced by variation in availability of ribosomal machinery.

What if you could flip a genetic switch to silence a gene, then turn it back on with a simple drug? For researchers, gene-switch tools offer that kind of control—and a new system called Cyclone may ...

SAR446268 is a one-time adeno-associated viral gene therapy that delivers a vectorized RNA interference to silence DMPK expression. The Food and Drug Administration (FDA) has granted Fast Track ...