Researchers have achieved the most detailed view yet of how DNA folds and functions inside living cells, revealing the physical structures that ...
Evo’s success wasn’t limited to proteins. When they tested a different toxin that had an RNA-based inhibitor, the system ...
Weill Cornell Medicine and New York Genome Center researchers, in collaboration with Oxford Nanopore Technologies, have developed a new method to assess on a large scale the three-dimensional ...
Understanding how long non-coding RNAs (lncRNAs) regulate gene expression and genome structure remains a major challenge in ...
In our bodies, there are trillions of cells. From white blood cells to skin cells, each type has its own specific function which helps us perform tasks and survive. But what makes up these cells and ...
Although existing CRISPR-Cas-based imaging methods can target endogenous genomic sequences, their applications are limited by ...
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Mapping 'dark' regions of the genome illuminates how cells respond to their environment
Led by postdoctoral fellow Brian Cosgrove, they made hydrogels that mimic tissues of different stiffness and cultured cells on these gels. The researchers then used sequencing tools to quantify RNA ...
Scientists at the MRC Weatherall Institute of Molecular Medicine, University of Oxford, have achieved the most detailed view yet of how DNA folds and functions inside living cells, revealing the ...
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