PHILADELPHIA -- Researchers long thought that only one strand of a double-stranded microRNA can silence genes. Though recent evidence has challenged that dogma, it's unclear what the other strand does ...
Among the large, diverse set of mammalian long noncoding RNAs (lncRNAs), long noncoding primary microRNAs (lnc-pri-miRNAs) are those that host miRNAs. Whether lnc-pri-miRNA loci have important ...
microRNAs (miRNAs) are essential regulators of gene expression in diverse biological processes and disease states. They are short 22-nt noncoding RNAs that bind to mRNA targets via partial base ...
Potential of Field Is Catalyst for Emerging Diagnostic and Therapeutic Strategies As key regulators of gene expression and cellular machinery, microRNAs may be the most significant discovery in ...
Until now it was held that miRNAs—noncoding snippets of RNA, only a few nucleotides long—work exclusively by suppressing protein expression in dividing cells, including cancer cells. A study published ...
microRNAs (miRNA), non-coding RNA molecules, are widely known for regulating mRNA stability and translation. miR-10b has been increasingly implicated in the pathogenesis of gliomas, cancers of the ...
The 2024 Nobel Prize in Physiology or Medicine was awarded to Victor Ambros and Gary Ruvkun for their groundbreaking discovery of microRNA and its pivotal role in post-transcriptional gene regulation.
Victor Ambros and Gary Ruvkun were jointly awarded the 2024 Nobel Prize in physiology or medicine for discovering microRNA and its role in post-transcriptional gene regulation, as announced in Sweden ...
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