The tiny little powerhouses of our cells, the mitochondria, are unique among organelles because they carry their own tiny little genomes... | Genetics And Genomics ...

Doubly uniparental inheritance (DUI) of mitochondrial DNA (mtDNA) represents a rare and intriguing deviation from the standard model of strictly maternal inheritance. In bivalves, DUI manifests as the ...

Integrative and Comparative Biology, Vol. 59, No. 4 (October 2019), pp. 983-993 (11 pages) Despite wide-ranging implications of selfish mitochondrial DNA (mtDNA) elements for human disease and topics ...

A new study from deCODE genetics uses pedigrees and sequence data from 64,806 Icelanders to shed light on the rate and nature of mutations in mitochondrial DNA (mtDNA) and the peculiar dynamics of its ...

Management of mitochondrial-related heart disease relies on multidisciplinary care and symptom control, as targeted gene-editing therapies are limited.

Researchers have discovered a mechanism in DNA that regulates how disease-causing mutations are inherited. The team identified two enzymes that regulate a chemical modification, 6mA, in mitochondrial ...

In most eukaryotes, the inheritance of mitochondrion and its DNA (mtDNA) is strictly maternal, despite the fact that a spermatozoon can inject up to 100 functional mitochondria into the oocyte during ...

Scraps of DNA discarded by our neurons' power units are being absorbed into our nuclear genome far more frequently than assumed, potentially putting our brains at greater risk of developing ...

According to a recent AHA Scientific Statement, despite ongoing limitations, recent advances in genomic sequencing ...

Recombination occurs in human mitochondrial DNA, says a team from the Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, in a “proof of concept” paper in Science this week that ...