Nucleic acids are complex biological molecules that store and transmit genetic information in all living organisms. They are essential for the survival and reproduction of life on Earth. The two main ...

Since the discovery of the double-helical structure of DNA and postulation of the central dogma of molecular biology, stating that the flow of genetic information goes from DNA to RNA to protein, the ...

DNA, the blueprint of life, is best known for its fundamental role as genetic material—storing and transmitting biological information through the precise sequence of its bases. For decades, this ...

Nature encodes nucleic acids to assemble enormously complex and highly functional materials that form the foundation of life. To establish a similar code to construct synthetic, unnatural materials ...

The Nucleic Acids Institute is dedicated to uncovering the chemical and biological underpinnings of nucleic acid function, and to developing innovative nucleic acid-based therapies and applications.

Thioguanosine (shown as S in the sequence) is placed at nearby, non-complementary positions within a DNA duplex. When exposed to light or mild oxidants, the modified bases react to form a disulfide ...

Scientists developed a light-responsive artificial nucleic acid that enables reversible, controllable crosslinking within DNA, opening doors for nanomedicine, DNA nanotechnologies and drug delivery.

Quantification of nucleic acid concentrations is often performed by measuring light absorption in UV-VIS spectrometers. There are a few challenges faced in this measurement method. In UV-VIS ...