Protein folding is a critical process by which linear chains of amino acids adopt specific three‐dimensional conformations essential for biological function. In recent years, studies have increasingly ...

Demis Hassabis (CEO of Deep Mind) and John M. Jumper have useed artificial intelligence to predict the structure of almost all known proteins. David Baker has learned how to master life’s building ...

Proteins are long molecules that must fold into complex three-dimensional structures to perform their cellular functions. This folding process occasionally goes awry, resulting in misfolded proteins ...

Researchers in Class of 1942 Professor of Chemistry Matthew D. Shoulders' lab have uncovered a sinister hidden mechanism that ...

When a protein folds, its string of amino acids wiggles and jiggles through countless conformations before it forms a fully folded, functional protein. This rapid and complex process is hard to ...

Anyone who's tried to neatly gather a fitted sheet can tell you: folding is hard. Get it wrong with your laundry and the result can be a crumpled, wrinkled mess of fabric, but when folding fails among ...

The strategies biopharmaceutical manufacturers currently use to limit protein misfolding are complex, time-consuming, and generate low yields with only limited scalability. Covalent organic frameworks ...

The diagram illustrates the key stages of protein synthesis in a eukaryotic cell. It begins with transcription to produce pre-mRNA in the nucleus (1), followed by post-transcriptional modification (2) ...

By Vijay Kumar Malesu New mouse data reveal that ageing neurons struggle to clear synaptic proteins, shifting the burden to ...

"Science is teamwork. Lone wolves no longer exist," Peter Walter, researcher and professor at the University of California, San Francisco, and former president of the American Society for Biochemistry ...