The direct observation and quantification of G-quadruplex structures formed from DNA in human cells during the cell cycle demonstrate the biological importance of these structures and point towards ...

Like the aglets at the end of your shoelaces, protein-and-DNA assemblies known as telomeres protect the ends of your chromosomes from fraying. In work with potential implications for the development ...

There is no more iconic image in biology than that of DNA's double-stranded helix, which coils and supercoils on itself to form dense chromosomes. But a quite different, square-shaped type of DNA ...

Artificial intelligence has just redrawn the map of our genome’s control room, revealing hundreds of thousands of tiny DNA ...

DNA, the genetic material compacted in chromosomes, stores information to regulate all the cell processes in the body. Two decades ago, in addition to the widely known Watson-Crick double helix model ...

The world’s most famous molecule – the DNA double helix – sometimes doubles up again. Researchers have now found this quadruple-stranded form in healthy human cells for the first time. Four-stranded ...

G-quadruplexes (G4s) are non-canonical structures formed by guanine-rich nucleic acids, increasingly implicated in transcriptional control, replication dynamics and genome stability at telomeres and ...

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