Physicists introduce phase contrast to electron microscopy, delivering sharper images of our body's tiniest proteins

Nearly 100 years ago, a seemingly simple discovery revolutionized the microscope. The introduction of phase contrast, which ...
C&EN

A new, ultrabright laser powers a cryo-EM advance 15 years in the making

Fifteen years ago, physicists worked out a method to increase image contrast by hitting the electron imaging beam with an ...
Nature

Coherent linking between confocal amplitude image and confocal phase image in dual-comb microscopy

We propose a method for integrating confocal amplitude and phase images obtained through dual-comb microscopy (DCM). DCM combines the benefits of confocal laser microscopy and quantitative phase ...
Nature

Smart hybrid microscopy for cell-friendly detection of rare events

Fluorescence microscopy offers unparalleled access to the spatial organization and dynamics of biological events in living samples, yet capturing rare processes over extended durations remains ...