Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to Parkinson's to ALS and beyond, is expected to double every 20 years. Though ...
Researchers developed a high-resolution spatial proteomics method to map protein and sugar changes in the brain. The study ...
Researchers identify the Munc13-1 protein as a crucial molecular pathway for working memory, linking calcium signaling to synaptic strengthening.
Salk researchers create epigenetic atlas of cell type-specific changes in the aging mouse brain, representing eight different brain regions and 36 different cell types to show clear epigenetic ...
Researchers create a massive single-cell atlas of the aging mouse brain, revealing how epigenetic changes and "jumping genes" drive neurodegeneration.
Hormone levels fluctuate like the tides, ebbing and flowing according to carefully orchestrated cycles. These hormones not only influence the body, but can cross into the brain and shape the behavior ...
A large-scale atlas of mouse brain cells has revealed that aging does not affect all brain cell types equally. Some cell populations show dramatic shifts in gene activity between youth and old age, ...
As organisms grow older, changes in the bacteria living inside the digestive system can directly cause the memory loss ...