DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave.

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

For successful cell division, chromosomal DNA needs to be packed into compact rod-shaped structures. Defects in this process can lead to cell death or diseases like cancer. A new study has shown how ...

DNA isn't just a long string of genetic code, but an intricate 3D structure folded inside each cell. That means the tools used to study DNA need to be just as sophisticated-able to read not only the ...

In its effort to correlate genomic structure with gene function, the 4D Nucleome Consortium (4DN), led by Job Dekker, Ph.D., ...

Two new landmark studies show how a seeming tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell. The work, published March 3 as two papers in ...

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They were hardly modest, these two brash young scientists who in 1953 declared to patrons of the Eagle Pub in Cambridge, England, that they had "found the secret of life." But James Watson and Francis ...