Many membrane proteins form multimers before they achieve a functional state and are transported to the plasma membrane of the cell. The stoichiometry of a complex is precisely regulated and is ...

Traditional vaccination approaches practically eradicated several extremely infectious diseases around the world. Despite their success, these conventional approaches are insufficient in their ability ...

Advances in technology are accelerating the development and manufacture of subunit vaccines, an established class of vaccines. As the name implies, subunit vaccines are based on a portion of the ...

"Our filovirus vaccines have demonstrated broad and robust immune responses in mice and up to 100% protection in non-human primates," stated Dr. Lehrer. "This further demonstration of extended ...

This vaccine type could greatly enhance COVID fight, especially in poor countries Highlights New crop of protein-based COVID vaccines expands the world's choices for jabs. Advantages of protein ...

In previous phase 1–2 clinical trials involving older adults, a subunit vaccine containing varicella–zoster virus glycoprotein E and the AS01 B adjuvant system (called HZ/su) had a clinically ...