Retinitis pigmentosa (RP) is a genetic eye disorder affecting around one in 5,000 people worldwide. It typically begins with ...

In patients with retinitis pigmentosa (RP), crucial cells in the retina known as rods and cones die over time; night ...

The expression of genes has to be very carefully controlled by cells; serious problems can arise when genes are expressed in the wrong places, at the wrong times, or at the wrong levels, for some ...

When a gene produces too much protein, it can have devastating consequences on brain development and function. Patients with an overproduction of protein from the chromodomain helicase DNA binding ...

In RNA molecules, the 5′ untranslated region (UTR) is located directly upstream of the start codon and plays a crucial role in post-transcriptional regulation by controlling RNA stability, cellular ...

Understanding glioblastoma survival: A SEER-based study of demographics and treatment. Real-world experience with vorasidenib in IDH-mutant gliomas: Tolerability, adverse events, and access in ...

Scientists at the University of Pittsburgh, together with colleagues at the University of Pittsburgh School of Medicine and University of Pittsburgh Cancer Institute, have identified how a long ...

Impact of variant allele frequency (VAF) of TP53 alterations and Signatera circulating tumor DNA (ctDNA) monitoring for patients (pts) with advanced urothelial carcinoma (aUC) treated with enfortumab ...