This systematic review investigates the high level of hypertension found among urban dwellers in West Africa and in the West African Diaspora in the Americas in relation to variants within the genes ...

The intra-renal renin–angiotensin system (RAS) has a crucial role in the regulation of renal function and the pathophysiology of hypertension. 1, 2 Activation of the intra-renal RAS was reported in ...

Several of the genes encoding elements of the renin-angiotensinogen system, including angiotensinogen (AGT), subtype I of the angiotensin II receptor (AGTR1), angiotensin converting enzyme (ACE), and ...

A study published in BMC Nephrology explored whether serum angiotensinogen could serve as a reliable biomarker to identify ...

Jennifer M. Jones, Jung-Jun Park, Jennifer Johnson, Dave Vizcaino, Brian Hand, Robert Ferrell, Matthew Weir, Thomas Dowling, Thomas Obisesan, Michael Brown https ...

Patients with sickle cell anemia (SCA) and persistent albuminuria (PA) exhibited significantly higher levels of urinary angiotensinogen (AGT). “What we’re most excited about is that urinary ...

In this first-in-human, placebo-controlled study, patients who received zilebesiran showed dose-dependent decreases in serum angiotensinogen levels and 24-hour ambulatory BP after a single ...

Angiotensinogen plays a key role in hypertension pathogenesis. Zilebesiran, an RNA interference therapeutic agent that inhibits angiotensinogen production, is being studied for hypertension treatment.

Association between treatment facility volume and mortality in patients with glioblastoma (GBM): A large national analysis. This is an ASCO Meeting Abstract from the 2018 ASCO Annual Meeting I. This ...

Urinary angiotensinogen levels at the time of hospital admission predicted acute decompensated heart failure patients' risk of developing acute kidney injury with considerable accuracy, scientists ...

SHANGHAI, April 21, 2025 /PRNewswire/ -- Rona Therapeutics, a biotechnology company pioneering innovative RNA-targeted therapies, announced that the Investigational New Drug (IND) application for ...