A new study published in Nature Structural & Molecular Biology reveals how the fundamental enzyme called DNA polymerase delta operates during DNA replication, making a copy of the genetic code that ...

When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key ...

A research team has analyzed the three-dimensional structure of a protein that suppresses the development of colorectal polyposis, MUTYH, at the atomic level and clarified the repair mechanism for DNA ...

Life depends on double-stranded DNA unwinding and separating into single strands that can be copied for cell division. Scientists have determined at atomic resolution the structure of machinery that ...

DNA, or deoxyribonucleic acid, is the hereditary material found in nearly all living organisms. It carries the genetic instructions for the development, functioning, growth, and reproduction of all ...

Photos and letters from the archives show how James Watson and Francis Crick raced to uncover the double helix structure of DNA. Science Photo Library DNA is the molecule that contains the hereditary ...

Reactive oxygen species produced inside cells oxidize DNA, and when the guanine base in DNA undergoes oxidation, 8-oxoguanine base is produced. Normally, guanine pairs with cytosine, but 8-oxoguanine ...