Amidst the debate around whether pathogenic mutations of presenilin harm cells by a gain of toxic function, or a loss of essential normal function (see ARF related news story), new results with ...

In a recent Molecular Therapy: Nucleic Acids study, researchers demonstrate enhanced loss-of-function editing of clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated ...

Scientists at deCODE genetics, a subsidiary of Amgen, reveal today in Nature Genetics associations between rare loss-of-function variants in two genes and bipolar disorder. REYKJAVIK, Iceland, March ...

In this paper, we investigate the importance of different loss functions when estimating and evaluating option pricing models. Our analysis shows that it is important to take into account parameter ...

In recent years, the use of computer algorithms for identifying specific objects within images, called “image segmentation,” has become popular in medical image analysis, helping doctors diagnose ...

A new study highlights how important uninterrupted sleep is to recovery after a traumatic brain injury, finding that ...

Q: I am considered obese and have kidney disease. Can weight loss surgery be an option to help improve kidney function? A: Chronic kidney disease, or chronic kidney failure, is the body's gradual loss ...

A new study showed that mild or greater hearing loss in midlife was associated with a 71% higher risk of dementia over a ...