A primary goal in designing new cancer therapies is to target cancer cells specifically and, at the same time, spare healthy tissues. Cancer cells exhibit, among others, characteristic features in the ...

There is growing evidence that inflammation is a central and reversible mechanism through which obesity promotes cancer risk and progression. Locally, hyperadiposity is associated with altered adipose ...

Stay up to date on the latest science with Brush Up Summaries. What Is the Tumor Microenvironment? The tumor microenvironment (TME) is a local area created and dominated by a tumor that contains ...

Interrogating PI3K to induce PD-L1 expression in oral carcinoma. This is an ASCO Meeting Abstract from the 2018 ASCO Annual Meeting I. This abstract does not include a full text component.

What drives tumor growth? Is it a few rogue cells imposing their will upon healthy tissue, or diseased tissue bringing out the worst in otherwise peaceable cells? Or is it a back-and-forth, a dialogue ...

The labyrinth of jumbled blood vessels in the tumor microenvironment remains one of the toughest blockades for cellular therapies to penetrate and treat solid tumors. Now, in a new study published ...

The tumor microenvironment is a battleground where infiltrating immune cells either subdue or promote a cancer, all while cancer cells try to dampen the body’s defenses. 1,2 Scientists have studied ...

MIAMI, FLORIDA (EMBARGOED UNTIL NOV. 9, 2023, AT 11 A.M. ET) – A multicenter study led by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine ...

BUFFALO, N.Y. -- Gail Seigel, PhD, research assistant professor in the University at Buffalo Department of Physiology and Biophysics, will be part of a group of researchers taking part in the new ...

Imunon’s IL-12 gene therapy IMImuNN-001 converts the tumour microenvironment from “cold” to “hot” by both, halting immunosuppressive makers, and stimulating anti-tumour cells in advanced ovarian ...

This paper analyzes the physical, spiritual and cultural mechanisms of the national ventilation techniques in Chinese traditional microenvironment design and points out that traditional ventilation ...