Protein design (or protein engineering) is a technique by which proteins with enhanced or novel functional properties are created. Proteins can be engineered by rational design, which typically uses ...

High School Sports High School Sports Queen’s Grant, all underclassmen, wins Observer Sweet 16 after historic state title Queen’s Grant, with no seniors, caps a 35-3 season by winning the Observer ...

We missed Cardi B’s request for “down south food” while in Dallas. But here are our recommendations for next time.

Dell Curry will be honored by having his Hornets jersey retired Thursday. All three of his kids spoke exclusively to The Charlotte Observer. Part of the McClatchy Media Network ...

A few passing clouds. Low 57F. Winds NNE at 5 to 10 mph.

Outspoken N.C. State coach Will Wade vows continued improvement for the Wolfpack after early NCAA Tournament loss: “This will be the worst team we have at NC State, right here.” Part of the McClatchy ...