Stem-cell memory T (TSCM) cells are a rare subset of immune cells with the ability to self-renew, persist long term, and ...

Reimagining clinical trial engagement through community partnership, pragmatic design, and artificial intelligence–enabled ...

bDepartment of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China cDepartment of Clinical Epidemiology and Evidence-Based Medicine, ...

Whole-blood transfusion has recently gained favor in the management of severe hemorrhage; however, data from large clinical trials evaluating its clinical effectiveness and safety are lacking. We ...

The impact of intensive blood pressure (BP) control on cognitive function in East Asian populations remains uncertain. We aimed to assess the effect of a lower systolic BP target on global cognitive ...

Researchers at The Hospital for Sick Children (SickKids), working with international collaborators and youth and family caregivers, have developed a child- and youth-centred global standard for ...

As a public health practitioner, you are considering how public health interventions might encourage individuals and families to reduce their salt intake to improve blood pressure among local ...

A new study in the American Journal of Preventive Medicine reports findings from a randomized controlled trial—the gold standard study design in health research—showing that promoting drinking water ...

The FDA is raising the bar for approval of CAR T-cell therapies in oncology. Under plans outlined by the FDA’s biologics chief Vinay Prasad, M.D., the agency will require developers of many CAR-Ts to ...

For traditional approval, CAR T therapies will need to establish superiority over current standard treatments, including already-approved CAR T products. The FDA is eyeing regulatory changes that ...