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Metabolic changes and side effects of total parenteral nutrition
Vein irritation: can give higher osmolarity in central line vs peripheral Infection: meticulous care of TPN lines is required Hepatic steatosis: when glucose calories exceed caloric req, liver begins to store excess sugar as fat → AST and ALT rise Hypercarbia/hypercapnia: if more carbs are given than needed, metabolism of sugar produces CO2 ...
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